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Table 6 DSC data of the peak values of the pure drug and the mixture of drug and excipients

From: Development, optimization and pharmacokinetic evaluation of biphasic extended-release osmotic drug delivery system of trospium chloride for promising application in treatment of overactive bladder

S. no

Ingredients

API: excipient ratio

Peak value (°C)

1

Trospium chloride (API)

272.89

2

API + Povidone NF (Kollidon K30)

1:0.5

265.78

3

API + Hydroxypropyl Cellulose NF (Nisso HPC SSL)

1:0.1

270.17

4

API + Polyethylene glycol 3350 NF (Polyglykol 3350 P)

1:0.1

266.61

5

API + Cellulose Acetate NF (CA-398–10)

1:2

272.09

6

API + Polyethylene Oxide NF (Polyox N80)

1:10

272.18

7

API + Mannitol USP (Pearlitol SD 200)

1:2

272.09

8

API + Hydroxy ethyl cellulose NF (Natrosol 250 L)

1:0.25

272.81

9

API + Magnesium Stearate NF (Veg grade)

1:0.25

267.51

10

API + Iron Oxide Yellow NF (Sicovit Yellow)

1:0.1

272.06