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Table 2 Thrombolytic activity of the investigated extracts of M. dispermus leaves and stem barks

From: Phytochemical and pharmacological investigations of different extracts of leaves and stem barks of Macropanax dispermus (Araliaceae): a promising ethnomedicinal plant

Group Mean ± SEM % of clot lysis
Control 3.71 ± 0.44
Standard (streptokinase) 64.72 ± 1.88***
MDML (10 mg/ml) 27.36 ± 3.83**
MDML (8 mg/ml) 25.01 ± 3.97
MDML (6 mg/ml) 23.44 ± 3.32**
MDML (3 mg/ml) 9.38 ± 1.63
MDML (1.5 mg/ml) 7.81 ± 0.88
MDHL (10 mg/ml) 37.05 ± 2.69***
MDHL (8 mg/ml) 36.27 ± 1.70***
MDHL (6 mg/ml) 27.89 ± 2.18***
MDHL (3 mg/ml) 22.89 ± 1.79***
MDHL(1.5 mg/ml) 12.62 ± 1.89
MDTL (10 mg/ml) 15.95 ± 1.96*
MDTL(8 mg/ml) 13.62 ± 1.64*
MDTL (6 mg/ml) 12.28 ± 1.46*
MDTL (3 mg/ml) 10.49 ± 1.04*
MDTL (1.5 mg/ml) 9.89 ± 0.96*
MDCL(10 mg/ml) 29.81 ± 1.71***
MDCL (8 mg/ml) 21.17 ± 1.92**
MDCL (6 mg/ml) 15.61 ± 1.45**
MDCL (3 mg/ml) 12.32 ± 0.89***
MDCL (1.5 mg/ml) 9.52 ± 1.03*
MDEL (10 mg/ml) 16.15 ± 1.36**
MDEL (8 mg/ml) 8.49 ± 1.41
MDEL (6 mg/ml) 7.85 ± 0.73
MDEL (3 mg/ml) 6.26 ± 0.93
MDEL (1.5 mg/ml) 3.52 ± 0.90
MDMS (10 mg/ml) 42.21 ± 1.84***
MDMS (8 mg/ml) 29.27 ± 2.71**
MDMS (6 mg/ml) 26.89 ± 2.73**
MDMS (3 mg/ml) 18.40 ± 1.66**
MDMS (1.5 mg/ml) 17.89 ± 2.36*
  1. The results were expressed in Mean ± SEM (standard mean error) *p < 0.05, **p < 0.01, and ***p < 0.001 were considered as statistically significant. The statistical analysis followed by one-way analysis of variance (Dunnett’s test) compared to the control. MDML = Crude methanol extract of M. dispermus leaves, MDHL = n-hexane fraction of crude methanol extract of M. dispermus leaves, MDTL = Carbon tetrachloride fraction of crude methanol extract of M. dispermus leaves, MDCL = Chloroform fraction of crude methanol extract of M. dispermus leaves, MDEL = Ethyl acetate fraction of crude methanol extract of M. dispermus leaves, MDMS = Crude methanol extract of M. dispermus stem barks