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Table 3 Cytotoxic activity of the multiple extracts of M. dispermus leaves and stem barks

From: Phytochemical and pharmacological investigations of different extracts of leaves and stem barks of Macropanax dispermus (Araliaceae): a promising ethnomedicinal plant

Sample Equation R2 LC50 (µg/ml)
Standard (vincristine sulfate) y = 4.978x + 49.32 R2 = 0.820 0.14
MDML y = 0.028x + 2.916 R2 = 0.914 1681.57
MDHL y = 0.021x + 4.166 R2 = 0.806 2579.33
MDTL y = 0.018x + 5 R2 = 0.677 2500.00
MDCL y = 0.054x + 48.75 R2 = 0.874 23.15
MDEL y = 0.059x + 45 R2 = 0.898 84.75
MDAL y = 0.082x + 22.08 R2 = 0.957 340.49
MDMS y = 0.045x + 48.33 R2 = 0.915 37.11
  1. The results were expressed in Mean ± SEM (standard mean error) *p < 0.05, **p < 0.01, and ***p < 0.001 were considered as statistically significant. The statistical analysis followed by one-way analysis of variance (Dunnett's test) compared to the control. MDML = Crude methanol extract of M. dispermus leaves, MDHL = n-hexane fraction of crude methanol extract of M. dispermus leaves, MDTL = Carbon tetrachloride fraction of crude methanol extract of M. dispermus leaves, MDCL = Chloroform fraction of crude methanol extract of M. dispermus leaves, MDEL = Ethyl acetate fraction of crude methanol extract of M. dispermus leaves, MDAL = Aqueous fraction of crude methanol extract of M. dispermus leaves, MDMS = Crude methanol extract of M. dispermus stem barks