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Table 9 Percent decrease in rectal temperature of all test samples of M. dispermus leaves and stem barks on brewer’s yeast-induced pyrexia test

From: Phytochemical and pharmacological investigations of different extracts of leaves and stem barks of Macropanax dispermus (Araliaceae): a promising ethnomedicinal plant

Group Percent decrease in rectal temperature (%) after drug treatment
1 h 2 h 3 h 4 h
Paracetamol (150 mg/kg) 65.57 81.97 91.8 100
MDML (200 mg/kg) 30.71 61.43 78.57 70.71
MDML (400 mg/kg) 33.33 70.51 88.46 75.64
MDHL (200 mg/kg) 12.99 24.29 52.54 69.49
MDHL (400 mg/kg) 29.82 69.3 89.47 95.61
MDTL (200 mg/kg) 17.07 78.05 71.54
MDTL (400 mg/kg) 30.83 79.17 98.33
MDCL (200 mg/kg) 50.00 74.71
MDCL (400 mg/kg) 54.79 80.85
MDEL (200 mg/kg) 28.72 44.62 63.59 70.77
MDEL (400 mg/kg) 36.31 62.42 89.81 96.82
MDAL (200 mg/kg) 42.71 46.35
MDAL (400 mg/kg) 22.05 63.59 75.38
MDMS (200 mg/kg) 6.61 60.33 56.2
MDMS (400 mg/kg) 20.42 76.76 83.8
  1. The results were expressed in Mean ± SEM (standard mean error) *p < 0.05, **p < 0.01, and ***p < 0.001 were considered as statistically significant. The statistical analysis followed by one-way analysis of variance (Dunnett's test) compared to the control. MDML = Crude methanol extract of M. dispermus leaves, MDHL = n-hexane fraction of crude methanol extract of M. dispermus leaves, MDTL = Carbon tetrachloride fraction of crude methanol extract of M. dispermus leaves, MDCL = Chloroform fraction of crude methanol extract of M. dispermus leaves, MDEL = Ethyl acetate fraction of crude methanol extract of M. dispermus leaves, MDAL = Aqueous fraction of crude methanol extract of M. dispermus leaves, MDMS = Crude methanol extract of M. dispermus stem barks, ‘–’ indicates the reduction of temperature didn’t occur at a time interval