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Table 2 Summary of Validation Parameters

From: Simultaneous quantification of empagliflozin, linagliptin and metformin hydrochloride in bulk and synthetic mixture by RP–LC method

Parameter

MET

LINA

EMPA

Range (µg/ml)

50–500

0.25–2.5

0.5–1

Limit of detection (LOD)

5.65

0.04

0.03

Limit of quantification (LOQ)

17.12

0.12

0.10

Retention time

2.01

3.2

14.5

Accuracy (%)

100.65–101.35

99.33–100.57

99.98–100.81

Precision (%RSD)

   

Intraday (n = 3)

0.21–1.12

0.20–1.27

0.29–1.69

Interday (n = 3)

1.10–1.91

0.76–1.53

0.70–1.78

Instrumental precision (%RSD)

   

Repeatability (n = 6)

1.12

0.97

0.62