Table 4 Equations for optimization of response surface method
From: Response surface method for optimization of prepared satranidazole powder layered pellets
Sl. no | Name of equation | Subsequent equation |
|---|---|---|
1 | ||
a | Final equation in terms of coded factors for drug release at 2 h | Drug release at 2 h = + 0.99 − 0.035 * X1a − 0.80 * X2b |
b | Final equation in terms of actual factors for drug release at 2 h | Drug release at 2 h = + 2.694–2.114–003 * X1a − 0.080 * X2b |
2 | ||
a | Final equation in terms of coded factors for drug release at 6 h | Drug release at 6 h = + 12.13 + 3.63 * X1a − 6.95 * X2b |
b | Final equation in terms of actual factors for drug release at 6 h | Drug release at 6 h = + 15.155 + 0.217 * X1a − 0.695 * X2b |
3 | ||
a | Final equation in terms of coded factors for drug release difference at 10 h | Drug release difference at 10 h = + 20.29 + 8.65 * X1a − 10.91* X2b |
b | Final equation in terms of actual factors for drug release difference at 10 h | Drug release difference at 10 h = + 16.198 + 0.518 * X1a − 1.090 * X2b |
4 | ||
a | Final equation in terms of coded factors for mean dissolution time | Mean dissolution time = + 9.06 − 0.40 * X1a + 0.60 * X2b |
b | Final equation in terms of actual factors for mean dissolution time | Mean dissolution time = + 9.044 − 0.0239 * X1a + 0.0604* X2b |