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Table 4 Brine shrimp cytotoxicity of crude root, root bark, and root tuber extracts of Acanthus polystachyus, Keetia gueinzii, and Rhynchosia elegans

From: Qualitative and quantitative phytochemical composition, antimicrobial activity, and brine shrimp cytotoxicity of different solvent extracts of Acanthus polystachyus, Keetia gueinzii, and Rhynchosia elegans

Plant species Part used Solvent used Mortality per test dose LC50 (µg/ml) Toxicity
10 µg/ml 100 µg/ml 1000 µg/ml Meyer’s toxicity index [41] Clarkson’s toxicity index [44]
A. polystachyus Roots Acetone 0 1 50 195.17 (109.11–349.08) Toxic Moderately toxic
   Distilled water 0 0 0 No death Non-toxic Non-toxic
   Methanol 0 6 49 174.26 (93.37–325.23) Toxic Moderately toxic
K. gueinzii Root bark Acetone 0 0 0 No death Non-toxic Non-toxic
   Distilled water 0 0 3 148,735,210.7 (2,807,216.20–7,880,462,816) Non-toxic Non-toxic
   Methanol 0 0 1 1.0 × 1016 (2.0 × 1012–5.1 × 1019) Non-toxic Non-toxic
R. elegans Root tuber Acetone 0 2 50 175.77 (98.27–314.39) Toxic Moderately toxic
   Distilled water 0 0 45 422.09 (199.52–893.59) Toxic Moderately toxic
   Methanol 0 5 50 168.76 (94.35–301.85) Toxic Moderately toxic
1% DMSO 0 0 0 No death Non-toxic Non-toxic
Vincristine sulphate 8 31 50 45.77 (19.75–106.06) Toxic Highly toxic