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Table 6 Binding parameters of the phytocompounds and the standard references with the amino acid residues at the active binding site of furin

From: Computational guided identification of potential leads from Acacia pennata (L.) Willd. as inhibitors for cellular entry and viral replication of SARS-CoV-2

Sl. No Compound ID Conventional hydrogen bonding Hydrophobic interaction Carbon-hydrogen interaction Electrostatic interaction
1 C_18 ASP191, SER368, THR365, ARG193, FMT601, ASN295
2 C_4 ARG197, THR365, FMT601   HIS194 ARG298
3 C_5 HIS364, THR365, ASN295 FMT601 ARG298
4 PGPRTRA ASN295, FMT601, SER368, HIS194, LEU227, GLY229 ASP258, GLU299
5 Naphthofluorescein HIS194, SER368 LEU227