Table 1 List out some of U.S FDA approved clinical drugs for various human diseases obtained from marine sources
Compound name | Marine organism | Molecular target | Indication | Approval date |
|---|---|---|---|---|
Trabectedin | Tunicate | Tunicate DNA (minor groove) | Soft tissue sarcoma and ovarian cancer | October 23, 2015 |
Brentuximab vedotin | Mollusk/cyanobacteria | CD30, microtubules | Anaplastic large T‑cell systemic malignant lymphoma, Hodgkin’s disease | August 19, 2011 |
Eribulin mesylate | Sponge | Microtubules | Metastatic breast cancer 0 | November 15, 2010 |
Omega‑3‑acid ethyl esters | Fish | Triglyceride‑producing enzymes | Hypertriglyceridemia | November 10, 2004 |
Ziconotide | Cone snail | DNA polymerase | Severe and chronic pain | December 28, 2004 |
Vidarabine | Sponge | Viral DNA polymerase | Herpes simplex virus infection | 1976 current status: Discontinued |
Cytarabine | Sponge | DNA polymerase | Leukemia | 1969 |