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Table 1 Optimized chromatographic conditions

From: Method development and validation for Cabotegravir and Rilpivirine by using HPLC and its degradants are characterized by LCMS and FTIR

Stationary phase

Symmetry C18 (150 × 4.6 mm, 3.5µ)

Carrying phase

Acetonitrile: 0.1% formic acid (80:20)

Injection volume

10 µL

Flow rate

1.0 ml/min

Column temperature

25 °C

Wavelength

231 nm

Run time

5 min

RT of Rilpivirine

2.050 min

RT of Cabotegravir

3.942 min