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Table 9 FTIR data of Cabotegravir, Rilpivirine, and its degradation products

From: Method development and validation for Cabotegravir and Rilpivirine by using HPLC and its degradants are characterized by LCMS and FTIR

S. no

API 1

API 2

DP1

DP2

DP3

DP4

Region (cm − 1)

Assignment

1

3400

3502

3406.8

3515.3

3489.5

3488.1

35003300

NH stretching

3328.5

3325.4

3318.2

3327.8

3357.1

3345.6

2

3157.6

3161.9

3162.3

3222.8

3228.3

32003000

CH Alkene stretching

3

2897.8

2868.2

28403000

CH Aliphatic stretching

4

2235.7, 2148.3

2236.2, 2152.5

2257.3

2368.1

2354

C≡N Stretching

5

1722.8

1725.3

1727.6

1737.1

16801630

C=O Stretching (Amides)

6

1487.8

16001450

C≡C Stretching

7

1287.8

1025.5

1288.6

1028.7

1287.9

1258.3

13501000

CN Stretching

1051.7

1057.1

1087.4

1049.3