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Table 2 Biochemical parameters of normal and diabetic animals on 7th day post-treatment

From: In vitro, acute and subchronic evaluation of the antidiabetic activity of Atractylis flava Desf n-butanol extract in alloxan-diabetic rats

Parameters

Normal control

Diabetic control

BEAF (500 mg/kg)

Glibenclamide (5 mg/kg)

Liver profile

    

ASAT(U/L)

141 ± 4.23

143.2 ± 6.77

187.6 ± 5.98

242.8 ± 3.36 **

ALAT(U/L)

78.3 ± 6.12

80.8 ± 8.76

98.5 ± 8.86

172.4 ± 9.66 **

Renal profile

    

Urea (mg/L)

0.28 ± 0.01

0.77 ± 0.51*

0.32 ± 0.01

0.32 ± 0.01

Creatinine (mg/L)

3.45 ± 1.71

6.30 ± 0.16**

3.78 ± 0.20

3 ± 0.08

Lipid profile

   

Cholesterol (mmol/L)

0.97 ± 1.10

02.03 ± 0.05**

01.03 ± 0.05

1.08 ± 0.05

Triglycerides (mmol/L)

0.62 ± 0.05

2.14 ± 0.15**

1.14 ± 0.15

1.30 ± 1.25

HDL-cholesterol (mmol/L)

0.60 ± 0.06

0.24 ± 0.06**

0.54 ± 0.06

0.77 ± 2.10

LDL-cholesterol (mmol/L)

0.10 ± 0.11

0.66 ± 0.01**

0.26 ± 0.01

0.18 ± 1.24

Blood glucose (g/L)

0.87 ± 0.13

3.68 ± 0.05**

1.89 ± 0.23

1.62 ± 0.35

  1. Each value represents the mean ± SEM n = 5. *P < 0.05; **P < 0.01 versus normal control (ANOVA followed by Dunnett’s test)