Future Journal of Pharmaceutical Sciences

Table 5 Method precision study

From: Impurity profiling method development and validation of metformin hydrochloride and teneligliptin hydrobromide hydrate in their combination tablet dosage form by using RP-HPLC with UV/PDA detector

S. no	API/impurity	Spl.1	Spl.2	Spl.3	Spl.4	Spl.5	Spl.6	%RSD
1	CYN	0.015	0.014	0.015	0.013	0.015	0.014	5.7
2	Melamine	0.003	0.004	0.004	0.004	0.004	0.004	10.6
3	TNG Impurity A	ND	ND	ND	ND	ND	ND	ND
4	TNG Impurity B	ND	ND	ND	ND	ND	ND	ND
5	Single max imp	0.082	0.084	0.076	0.085	0.0128	0.100	6.4
6	Total impurities	0.320	0.340	0.296	0.324	0.377	0.335	8.1

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