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Table 5 Method precision study

From: Impurity profiling method development and validation of metformin hydrochloride and teneligliptin hydrobromide hydrate in their combination tablet dosage form by using RP-HPLC with UV/PDA detector

S. no API/impurity Spl.1 Spl.2 Spl.3 Spl.4 Spl.5 Spl.6 %RSD
1 CYN 0.015 0.014 0.015 0.013 0.015 0.014 5.7
2 Melamine 0.003 0.004 0.004 0.004 0.004 0.004 10.6
3 TNG Impurity A ND ND ND ND ND ND ND
4 TNG Impurity B ND ND ND ND ND ND ND
5 Single max imp 0.082 0.084 0.076 0.085 0.0128 0.100 6.4
6 Total impurities 0.320 0.340 0.296 0.324 0.377 0.335 8.1