Future Journal of Pharmaceutical Sciences

Table 6 Intermediate precision study

From: Impurity profiling method development and validation of metformin hydrochloride and teneligliptin hydrobromide hydrate in their combination tablet dosage form by using RP-HPLC with UV/PDA detector

S. no	API/impurity	Spl.1	Spl.2	Spl.3	Spl.4	Spl.5	Spl.6	%RSD
1	CYN	0.013	0.015	0.014	0.015	0.014	0.014	5.3
2	Melamine	0.004	0.004	0.003	0.004	0.004	0.004	10.6
3	TNG Impurity A	ND	ND	ND	ND	ND	ND	ND
4	TNG Impurity B	ND	ND	ND	ND	ND	ND	ND
5	Single Mix. Imp	0.089	0.086	0.084	0.078	0.082	0.091	5.6
6	Total impurities	0.316	0.308	0.296	0.298	0.325	0.308	3.53

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