Molecule | BBB | CaCo2 | HIA | MRTD |
---|---|---|---|---|
N1 | − 0.329 | 1.460 | 100.00 | 0.264 |
N2 | − 0.515 | 1.388 | 97.962 | 0.268 |
N3 | 1.657 | − 0.224 | 67.746 | 0.506 |
N4 | 1.330 | 0.612 | 92.884 | 0.253 |
N5 | − 0.235 | 1.527 | 95.364 | 0.292 |
N6 | − 0.645 | 0.618 | 99.377 | 0.380 |
N7 | − 1.690 | 0.568 | 96.158 | 0.395 |
N8 | − 0.682 | 0.606 | 96.767 | 0.298 |
N9 | − 0.661 | 1.206 | 95.543 | 0.317 |
N10 | − 0.625 | 0.600 | 98.053 | 0.274 |
N11 | − 0.849 | 0.541 | 97.795 | 0.309 |
N12 | − 0.244 | 1.337 | 100.00 | 0.316 |
N13 | − 0.832 | 0.658 | 98.614 | 0.258 |
N14 | 1.520 | 1.138 | 73.264 | 0.858 |
N15 | 1.098 | − 0.323 | 89.430 | 0.263 |
N16 | 1.864 | − 0.261 | 38.246 | 0.297 |
N17 | 1.637 | − 0.156 | 59.978 | 0.310 |
N18 | 1.565 | 1.306 | 67.467 | 0.293 |
N19 | 1.763 | − 0.120 | 65.339 | 0.304 |
N20 | 1.739 | − 0.062 | 64.114 | 0.213 |
N21 | 1.820 | − 0.097 | 67.286 | 0.267 |
N22 | 2.044 | − 0.115 | 64.097 | 0.393 |
N23 | 1.952 | − 0.188 | 63.637 | 0.238 |
N24 | 1.726 | − 0.210 | 54.103 | 0.198 |
N25 | 1.918 | − 0.261 | 37.023 | 1.153 |
T | 1.522 | 1.223 | 74.912 | 0.445 |
R | 1.162 | − 0.598 | 83.660 | 0.216 |