Table 6 Pharmacokinetic parameters of pellet formulations
Pharmacokinetic parameter | MFH pellets | MFH Reference | GMP pellets | GMP Reference | PGH pellets | PGH Reference |
|---|---|---|---|---|---|---|
Cmax (ng/mL) | 1278.8 ± 7.27 | 1280 ± 8.93 | 190.2 ± 3.5 | 195.5 ± 2.9 | 296.8 ± 3.7 | 289.7 ± 2.8 |
[AUC0-∞] (ng.h/mL) | 22,393.53 | 22,769.1 | 1921.25 | 1976.375 | 3528.675 | 3946.125 |
Tmax (h) | 8.0 ± 0.00 | 8.0 ± 0.00 | 1.5 ± 0.00 | 1.5 ± 0.00 | 2.5 ± 0.00 | 2.5 ± 0.00 |