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Table 1 Response parameters

From: Pharmacoscintigraphic evaluation and antidiabetic efficacy of gliclazide-loaded 99mTc-labelled mucoadhesive microspheres

Std

Run

Factor 1 (X1)

Factor 2 (X2)

Response 1

Response 2

Response 3

A: polymer

B: cross-linking agent

DL

BA

DR

gm

gm

%

%

%

1

1

3(− 1)

2(− 1)

63.77

69.12

97.44

9

2

9(+ 1)

6(+ 1)

75.42

80.10

76.87

8

3

6(0)

6(+ 1)

79.37

82.13

78.87

6

4

9(+ 1)

4(0)

70.12

86.22

75.40

2

5

6(0)

2(− 1)

60.23

73.19

90.55

4

6

3(− 1)

4(0)

74

72.11

88.66

5

7

6(0)

4(0)

71.40

78.10

81.10

7

8

3(− 1)

6(+ 1)

80.72

76.50

81.20

3

9

9(+ 1)

2(− 1)

57.40

81.50

86.25

  1. Polymer: Musa balbisiana starch: Sodium alginate (1:1 in all formulation); Cross-linking agent: Calcium chloride; DL: Drug Loading; BA: Bio adhesion; DR: Drug release
  2. Coded values are in bracket; (X1) and (X2) are independent factors; (+ 1) = higher values; (0) = medium value and (− 1) = lower values