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Table 8 Effect of VMS against septic arthritis in different groups of animals

From: DoE approach for development of localized controlled release microspheres of Vancomycin for treatment of septic arthritis

Days

Diseased control group

Reference group

Test group

Clinical score

Knee size (mm)

Clinical score

Knee size (mm)

Clinical score

Knee size (mm)

0

0

4.2 ± 0.01

0

3.8 ± 0.02

0

4.0 ± 0.03

3

3

15.5 ± 0.02

3

14.8 ± 0.02

3

14.6 ± 0.03

6

3

16.2 ± 0.03

2

13.3 ± 0.04

2

12.4 ± 0.04

9

3

17.3 ± 0.02

2

11.9 ± 0.03

2

10.5 ± 0.02

12

3

18.5 ± 0.01

2

10.0 ± 0.02

2

9.5 ± 0.01

14

3

19.2 ± 0.04

2

8.5 ± 0.03

1

8.0 ± 0.05

  1. Data are represented as mean ± SD (n = 6), significantly different at P < 0.05 in comparison with diseased control group