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Table 8 Effect of VMS against septic arthritis in different groups of animals

From: DoE approach for development of localized controlled release microspheres of Vancomycin for treatment of septic arthritis

Days Diseased control group Reference group Test group
Clinical score Knee size (mm) Clinical score Knee size (mm) Clinical score Knee size (mm)
0 0 4.2 ± 0.01 0 3.8 ± 0.02 0 4.0 ± 0.03
3 3 15.5 ± 0.02 3 14.8 ± 0.02 3 14.6 ± 0.03
6 3 16.2 ± 0.03 2 13.3 ± 0.04 2 12.4 ± 0.04
9 3 17.3 ± 0.02 2 11.9 ± 0.03 2 10.5 ± 0.02
12 3 18.5 ± 0.01 2 10.0 ± 0.02 2 9.5 ± 0.01
14 3 19.2 ± 0.04 2 8.5 ± 0.03 1 8.0 ± 0.05
  1. Data are represented as mean ± SD (n = 6), significantly different at P < 0.05 in comparison with diseased control group