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Table 4 Precision studies

From: Stability-indicating method development and validation for the concurrent determination of darunavir, cobicistat, emtricitabine and tenofovir alafenamide by UPLC in bulk and tablet dosage forms

Parameter Results
TAF COBI FTC DRV
Method precision (for n = 6)
Mean %Assay 99.65 100.00 100.23 100.30
Mean % RSD of assay 0.2 0.8 0.3 0.9
System precision (for n = 6)
Mean of peak area 114,978 375,780 548,633 2,016,744
Mean % RSD of peak area 1.0 0.5 0.6 0.5
Intermediate precision (for n = 12)
Mean peak area 106,219 356,448 530,491 1,912,564
Mean % RSD of peak area 0.8 0.7 0.4 0.2
  1. TAF tenofovir alafenamide, COBI cobicistat, FTC emtricitabine, DRV darunavir, % percentage, RSD relative standard deviation, n no. of determinations