Table 1 List of commercial products active against influenza
From: Efficacy of the commercial plant products acting against influenza-a review
S.no. | Commercial product name | Plant name | Plant part used for extract | Rich Bioactive compound | Company | Influenza type | Influenza strains | Reference |
|---|---|---|---|---|---|---|---|---|
1 | COLD-FX® (CVT-E002) | Panax quinquefolium L | Root | Poly-furanosyl-pyranosyl-saccharide | Afexa Life Sciences Inc., Edmonton, Alberta, Canada | Influenza A H1N1,H3N2 and B | A/Johannesburg/82/96 (H1N1), A/Nanchang/93/95 (H3N2), B/Harbin/07/94 | [42] |
2 | CYSTUS052® | Cistus incanus L | Aerial parts | Polyphenol: Flavan-3-ols and proanthocyanidins | Dr. Pandalis NatUrprodukte GmbH & Co. KG, Glandorf, Germany | Influenza A H7N7,H1N1,H5N1 | A/FPV/Bratislava/79, (H7N7), A/PuertoRico/8/34(H1N1), A/Thailand/1(KAN1)/2004 (H5N1) | |
3 | Echinaforce® | Echinacea purpurea | Aerial parts and roots | Not mentioned | A. Vogel Bioforce AG, Roggwil, Switzerland | Influenza A H3N2 | Not mentioned | [47] |
Influenza A H3N2,H5N1,H7N7,H1N1 | A/Victoria/3/75 (H3N2), A/Thailand/KAN-1/2004 (H5N1), A/FPV/Bratislava/79 (H7N7), and A/PuertoRico/8/34, A/Hamburg/1/09 (H1N1) | [48] | ||||||
Influenza A H1/H3,and B | Not mentioned | [7] | ||||||
Influenza A H9N2 | A/chicken/Iran/772/1998 (H9N2) | |||||||
Influenza A H7N9 | A/Anhui/1/2013(H7N9) | [52] | ||||||
Influenza A H3N2 | A/Victoria/H3N2 (H3N2) | [53] | ||||||
4 | EPs® 7630 (Umckaloabo®) | Pelargonium sidoides DC | Roots | Polyphenol: Prodelphinidin, gallocatechin and epigallocatechin | Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe | Influenza A, H1N1, H3N2, H5N1 | A/New Caledonia/20/99 (H1N1), A/California/7/2004 (H3N2), A/Thailand/1(Kan1)/04 (H5N1), A/PuertoRico/8/34NS116-GFP (H1N1), A/Luxembourg/46/2009 (H1N1), A/PuertoRico/8/34 (H1N1),A/Luxembourg/663/2008(H1N1), A/Luxembourg/572/2008 (H1N1) A/Luxembourg/01/2005 (H3N2) | |
5 | Ladania067® | Ribes nigrum L | Leaves | Not mentioned | Dr. Pandalis NatUrprodukte GmbH & Co. KG, Glandorf, Germany | Influenza A, H1N1,H1N1 rec, H1N1 pan, H7N7 | A/Regensburg/D6/09 (H1N1) A/Puerto Rico/8/34 (H1N1rec), and A/Nordrhein-Wesfalen/173/2009 (H1N1pan) harboring the oseltamivir resistance mutation NA (H275Y), A/FPV/Bratislava/79 (H7N7) | |
6 | Mentofin® | Eucalyptus-peppermint essential oil | Leaves | Not mentioned | EWABO, Wietmarschen, Germany | Influenza A H9N2 | Not mentioned | |
7 | Oximacro® | Vaccinium macrocarpon Aiton | Fruit | PAC-A dimers and trimers | Biosfered S.r.l., Turin, Italy | Influenza A H1N1 and B | A/Puerto Rico/8/34 (H1N1), B/Lee/40 (B) | [67] |
8 | Sambucol® | Sambucus nigra L | Fruit, standardized black elderberry extract | Flavonoids (sam4,8) | Razei Bar Company in Jerusalem, Israel | Influenza A H1N1(human and animal strains) H3N2 and B | A/Texas 36/91, A/Singapore 6/86 (H1N1 human strains), A/Shangdong 9/93, A/Beijing 32/92(H3N2), B/Panama 45/90, B/Yamagata16/88, B/Ann Arbor 1/86(B) (A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91(H1Nanimal strains) | |
Avian Influenza A H5N1 | H5N1 (NIBRG-14) | [70] | ||||||
PharmaCare Europe Ltd., West Sussex, UK | Influenza A H9N2 | A/chicken/Iran/772/1998 (H9N2) | ||||||
Rubini® | Sambucus nigra L | Fruit, standardized black elderberry extract | Not mentioned | BerryPharma AG Leichlingen, Germany | Human Influenza A H5N1and B | A/Thailand/KAN-1/2004 (H5N1) and B/Massachusetts/71 | [73] | |
CJ-E® (Concentrated elderberry juice) | Sambucus nigra L | Fruit, standardized black elderberry extract | High molecular weight compounds with acidic polysaccharides | Bayernwald, Hengersberg, Germany | Influenza A H1N1 | A/NWS/33 (H1N1) | [74] |