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Table 1 List of commercial products active against influenza

From: Efficacy of the commercial plant products acting against influenza-a review Commercial product name Plant name Plant part used for extract Rich Bioactive compound Company Influenza type Influenza strains Reference
1 COLD-FX® (CVT-E002) Panax quinquefolium L Root Poly-furanosyl-pyranosyl-saccharide Afexa Life Sciences Inc., Edmonton, Alberta, Canada Influenza A H1N1,H3N2 and B A/Johannesburg/82/96 (H1N1), A/Nanchang/93/95 (H3N2), B/Harbin/07/94 [42]
2 CYSTUS052® Cistus incanus L Aerial parts Polyphenol: Flavan-3-ols and proanthocyanidins Dr. Pandalis NatUrprodukte GmbH & Co. KG, Glandorf, Germany Influenza A H7N7,H1N1,H5N1 A/FPV/Bratislava/79, (H7N7), A/PuertoRico/8/34(H1N1), A/Thailand/1(KAN1)/2004 (H5N1) [45, 46]
3 Echinaforce® Echinacea purpurea Aerial parts and roots Not mentioned A. Vogel Bioforce AG, Roggwil, Switzerland Influenza A H3N2 Not mentioned [47]
Influenza A H3N2,H5N1,H7N7,H1N1 A/Victoria/3/75 (H3N2), A/Thailand/KAN-1/2004 (H5N1), A/FPV/Bratislava/79 (H7N7), and A/PuertoRico/8/34, A/Hamburg/1/09 (H1N1) [48]
Influenza A H1/H3,and B Not mentioned [7]
Influenza A H9N2 A/chicken/Iran/772/1998 (H9N2) [49, 50]
Influenza A H7N9 A/Anhui/1/2013(H7N9) [52]
Influenza A H3N2 A/Victoria/H3N2 (H3N2) [53]
4 EPs® 7630 (Umckaloabo®) Pelargonium sidoides DC Roots Polyphenol: Prodelphinidin, gallocatechin and epigallocatechin Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe Influenza A, H1N1, H3N2, H5N1 A/New Caledonia/20/99 (H1N1), A/California/7/2004 (H3N2), A/Thailand/1(Kan1)/04 (H5N1), A/PuertoRico/8/34NS116-GFP (H1N1), A/Luxembourg/46/2009 (H1N1), A/PuertoRico/8/34 (H1N1),A/Luxembourg/663/2008(H1N1), A/Luxembourg/572/2008 (H1N1) A/Luxembourg/01/2005 (H3N2) [55, 56]
5 Ladania067® Ribes nigrum L Leaves Not mentioned Dr. Pandalis NatUrprodukte GmbH & Co. KG, Glandorf, Germany Influenza A, H1N1,H1N1 rec, H1N1 pan, H7N7 A/Regensburg/D6/09 (H1N1) A/Puerto Rico/8/34 (H1N1rec), and A/Nordrhein-Wesfalen/173/2009 (H1N1pan) harboring the oseltamivir resistance mutation NA (H275Y), A/FPV/Bratislava/79 (H7N7) [57, 58]
6 Mentofin® Eucalyptus-peppermint essential oil Leaves Not mentioned EWABO, Wietmarschen, Germany Influenza A H9N2 Not mentioned [63,64,65,66]
7 Oximacro® Vaccinium macrocarpon
Fruit PAC-A dimers and trimers Biosfered S.r.l., Turin, Italy Influenza A H1N1 and B A/Puerto Rico/8/34 (H1N1), B/Lee/40 (B) [67]
8 Sambucol® Sambucus nigra L Fruit, standardized black elderberry extract Flavonoids (sam4,8) Razei Bar Company in Jerusalem, Israel Influenza A H1N1(human and animal strains) H3N2 and B A/Texas 36/91, A/Singapore 6/86 (H1N1 human strains), A/Shangdong 9/93, A/Beijing 32/92(H3N2), B/Panama 45/90, B/Yamagata16/88, B/Ann Arbor 1/86(B) (A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91(H1Nanimal strains) [68, 69]
Avian Influenza A H5N1 H5N1 (NIBRG-14) [70]
PharmaCare Europe Ltd., West Sussex, UK Influenza A H9N2 A/chicken/Iran/772/1998 (H9N2) [49, 50]
Rubini® Sambucus nigra L Fruit, standardized black elderberry extract Not mentioned BerryPharma AG
Leichlingen, Germany
Human Influenza A H5N1and B A/Thailand/KAN-1/2004 (H5N1) and B/Massachusetts/71 [73]
CJ-E® (Concentrated elderberry juice) Sambucus nigra L Fruit, standardized black elderberry extract High molecular weight compounds with acidic polysaccharides Bayernwald, Hengersberg, Germany Influenza A H1N1 A/NWS/33 (H1N1) [74]