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Table 4 Docking of Caspase-8 with Olmesartan medoxomil

From: In silico assessment of chronic toxicity of a combination drug namely ‘Olmesartan medoxomil and Hydrochlorothiazide’, marketed in Bangladesh

Sl No

Type of amino acid

Full name

Hydrophobicity

pKa

Avg. isotopic displacement

1

Serine

A:Ser26

− 0.8

 

48.166

2

Leucine

A:Leu27

3.8

 

51.52

3

Aspartic acid

A:Asp28

− 3.5

3.9

52.136

4

Tyrocine

A:Tyr29

− 1.3

10

63.487