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Table 5 Cellular distribution (in %) in different cell cycle phases of SiHa cells after treatment with plant extract

From: Evaluation of anti-cancer potential of Excoecaria agallocha (L.) leaf extract on human cervical cancer (SiHa) cell line and assessing the underlying mechanism of action

Conc. of extract (µg/mL)

Cellular distribution (in %) in the different cell cycle phases

G0

G1

S

G2/M

0 (no treatment)

1.0 ± 0.15

40.5 ± 1.0

6.4 ± 0.02

8.9 ± 0.15

7.5

4.6 ± 0.35*

5.6 ± 0.30*

7.0 ± 0.04

16.8 ± 0.25*

15

2.3 ± 0.24

2.6 ± 0.07*

7.2 ± 0.20

30.8 ± 0.30*

30

0.5 ± 0.01

0.8 ± 0.01*

1.1 ± 0.01*

41.8 ± 0.40*

Cisplatin (5 µg/mL)

1.3 ± 0.02

55.7 ± 0.15*

13.2 ± 0.06

3.8 ± 0.025

Valinomycin (2 µg/mL)

2.4 ± 0.02

3.6 ± 0.07

5.3 ± 0.24

24.8 ± 0.01*

  1. Results are presented as mean ± SD of three sets of experiments
  2. *Significant difference in comparison to the control group (p < 0.05)