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Table 5 Cellular distribution (in %) in different cell cycle phases of SiHa cells after treatment with plant extract

From: Evaluation of anti-cancer potential of Excoecaria agallocha (L.) leaf extract on human cervical cancer (SiHa) cell line and assessing the underlying mechanism of action

Conc. of extract (µg/mL) Cellular distribution (in %) in the different cell cycle phases
G0 G1 S G2/M
0 (no treatment) 1.0 ± 0.15 40.5 ± 1.0 6.4 ± 0.02 8.9 ± 0.15
7.5 4.6 ± 0.35* 5.6 ± 0.30* 7.0 ± 0.04 16.8 ± 0.25*
15 2.3 ± 0.24 2.6 ± 0.07* 7.2 ± 0.20 30.8 ± 0.30*
30 0.5 ± 0.01 0.8 ± 0.01* 1.1 ± 0.01* 41.8 ± 0.40*
Cisplatin (5 µg/mL) 1.3 ± 0.02 55.7 ± 0.15* 13.2 ± 0.06 3.8 ± 0.025
Valinomycin (2 µg/mL) 2.4 ± 0.02 3.6 ± 0.07 5.3 ± 0.24 24.8 ± 0.01*
  1. Results are presented as mean ± SD of three sets of experiments
  2. *Significant difference in comparison to the control group (p < 0.05)