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Table 3 Effect of ethanolic extract of L. rugosa on liver function enzymes in paracetamol-induced hepatotoxicity in rats

From: Ameliorative effect of ethanolic extract of Limnophila rugosa (Scrophulariaceae) in paracetamol- and carbon tetrachloride-induced hepatotoxicity in rats

Treatment AST ALT ALP
Group-I (normal saline) 18.07 ± 0.32 49.66 ± 0.08 39.87 ± 0.08
Group-II (paracetamol 750 mg/kg) 83.56 ± 0.34** 101.08 ± 0.08** 98.09 ± 0.11**
Group-III (100 mg/kg Silymarin) 24.09 ± 0.45*** 55.76 ± 0.93*** 44.10 ± 0.34**
Group-IV (200 mg/kg) 51.09 ± 0.13* 72.03 ± 0.13** 68.42 ± 0.29*
Group-V (300 mg/kg) 39.15 ± 0.54* 67.32 ± 0.09** 53.76 ± 0.03*
  1. AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase
  2. Values are expressed as mean ± SEM, n = 6 and were estimated using one-way ANOVA followed by post hoc Tukey HSD test. Comparisons are made between (1) Group-I versus Group-II, (2) Group-II versus Group-III, IV and V. *p ˂ 0.05, **p ˂ 0.01, ***p ˂ 0.001 considered as significant