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Table 5 Effect of ethanolic extract of L. rugosa on liver function enzymes in CCl4-induced hepatotoxicity in rats

From: Ameliorative effect of ethanolic extract of Limnophila rugosa (Scrophulariaceae) in paracetamol- and carbon tetrachloride-induced hepatotoxicity in rats

Treatment AST ALT ALP
Group-I (normal saline) 22.47 ± 0.47 53.46 ± 0.88 44.07 ± 0.98
Group-II (CCl4 1.25 ml/kg) 103.62 ± 0.60** 133.63 ± 0.48** 177.06 ± 0.90**
Group-III (100 mg/kg silymarin) 36.46 ± 0.49** 62.85 ± 0.80*** 49.17 ± 0.19**
Group-IV (200 mg/kg) 76.54 ± 0.70* 93.96 ± 0.80** 114.07 ± 1.20**
Group-V (300 mg/kg) 56.28 ± 0.82** 82.59 ± 0.57** 96.18 ± 0.93**
  1. AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase
  2. Values are expressed as mean ± SEM, n = 6 and were estimated using one-way ANOVA followed by post hoc Tukey HSD test. Comparisons are made between (1) Group-I versus Group-II, (2) Group-II versus Group-III, IV and V. *p ˂ 0.05, **p ˂ 0.01, ***p ˂ 0.001 considered as significant