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Table 6 Effects of ethanolic extract of L. rugosa on some liver function indices of CCl4-induced hepatotoxic rats

From: Ameliorative effect of ethanolic extract of Limnophila rugosa (Scrophulariaceae) in paracetamol- and carbon tetrachloride-induced hepatotoxicity in rats

Treatment ALB DBL TBL Globulin TP TC
Group-I (normal saline) 56.59 ± 1.06 16.71 ± 0.42 15.60 ± 0.56 6.66 ± 0.24 60.03 ± 0.52 6.81 ± 0.35
Group-II (CCl4 1.25 ml/kg) 14.80 ± 0.23** 67.18 ± 0.16** 76.58 ± 0.41** 3.72 ± 0.09** 16.43 ± 0.41** 21.34 ± 0.65**
Group-III (100 mg/kg Silymarin) 45.62 ± 0.69*** 28.09 ± 0.67*** 22.76 ± 0.64** 5.64 ± 0.29* 54.46 ± 1.29*** 9.05 ± 0.20***
Group-IV (200 mg/kg) 29.16 ± 0.62* 49.21 ± 0.79* 56.30 ± 1.40** 4.86 ± 0.54 ns 35.88 ± 1.07** 17.57 ± 0.26**
Group-V (300 mg/kg) 39.32 ± 0.52** 37.62 ± 0.58** 37.43 ± 1.16** 4.53 ± 0.24 ns 45.87 ± 0.58** 11.20 ± 0.12**
  1. ALB: albumin; DBL: direct bilirubin; TBL: total bilirubin; TP: total protein; TC: total cholesterol
  2. Values are expressed as mean ± SEM, n = 6 and were estimated using one-way ANOVA followed by post hoc Tukey HSD test. Comparisons are made between (1) Group-I versus Group-II, (2) Group-II versus Group-III, IV and V. ns: nonsignificant, *p ˂ 0.05, **p ˂ 0.01, ***p ˂ 0.001 considered as significant