Skip to main content

Table 1 Effect of policosanol, atorvastatin, and silymarin treatments on serum triglyceride, total cholesterol, high density lipoproteins (HDL), and atherogenic index in HFD-fed animals

From: Therapeutic potential of policosanol in the concurrent management of dyslipidemia and non-alcoholic fatty liver disease

Serum parameters

Normal control

Disease control (HFD)

Policosanol 50 (mg/kg) + HFD

Policosanol 100 (mg/kg) + HFD

Atorvastatin30 (mg/kg) + HFD

Silymarin 100 (mg/kg) + HFD

Triglycerides (mg/dl)

98.56 ± 9.18

196.48 ± 18.65@@@

164.15 ± 20.11*

116.84 ± 13.04***

136.45 ± 13.14***

141.23 ± 15.56***

Total cholesterol (mg/dl)

58.94 ± 6.41

88.95 ± 11.29@@@

77.46 ± 8.38

64.96 ± 8.16***

66.05 ± 6.43***

70.86 ± 8.38**

High density lipoprotein (mg/dl)

36.15 ± 3.67

26.04 ± 2.86@@@

31.06 ± 3.51

34.92 ± 3.32**

34.59 ± 4.06**

32.48 ± 3.65*

Atherogenic Index

0.52 ± 0.06

2.01 ± 0.28@@@

1.74 ± 0.17

0.87 ± 0.11***

0.91 ± 0.12***

1.18 ± 0.13***

  1. Data are represented as mean ± SD (n = 6)
  2. @@@p < 0.001 compared with the normal control group
  3. *p < 0.05 compared with the HFD group
  4. **p < 0.01 compared with the HFD group
  5. ***p < 0.001 compared with the HFD group