Table 2 Effect of policosanol, atorvastatin, and silymarin treatments on AST, ALT, and ALP in the HFD-fed animals
Serum parameters | Normal control | Disease control (HFD) | Policosanol 50 (mg/kg) + HFD | Policosanol 100 (mg/kg) + HFD | Atorvastatin30 (mg/kg) + HFD | Silymarin 100 (mg/kg) + HFD |
|---|---|---|---|---|---|---|
AST (IU/L) | 45.45 ± 6.10 | 89.46 ± 9.89@@@ | 74.32 ± 9.01 | 52.56 ± 7.29*** | 59.84 ± 6.54*** | 56.18 ± 5.98*** |
ALT (IU/L) | 41.52 ± 5.69 | 78.14 ± 9.09@@@ | 70.65 ± 6.92 | 60.83 ± 12.18** | 52.42 ± 6.77*** | 50.64 ± 5.46*** |
ALP (IU/L) | 98.48 ± 15.64 | 167.51 ± 22.43@@@ | 150.83 ± 19.88 | 134.81 ± 13.13* | 120.12 ± 13.89*** | 125.56 ± 16.92** |
BILIRUBIN (IU/L) | 0.76 ± 0.18 | 1.77 ± 0.31@@@ | 1.39 ± 0.33 | 0.101 ± 0.27*** | 1.19 ± 0.11** | 0.91 ± 0.18*** |