Skip to main content

Table 11 Data for Oseltamivir phosphate tablet analysis

From: Quantification of organic volatile impurities in Oseltamivir phosphate drug substances by head space gas chromatography

Si. No Name of OVI Results (ppm) Approved values (ppm)
1 Methanol 108 Not more than 3000
2 Ethanol Not detected Not more than 5000
3 Acetonitrile 112 Not more than 410
4 IPA 120 Not more than 5000
5 DCM Not detected Not more than 600
6 MTBE Not detected Not more than 5000
7 Ethyl acetate Not detected Not more than 5000
8 THF Not detected Not more than 720
9 1,4-Dioxane Not detected Not more than 380
10 DMF Not detected Not more than 880
11 Toluene Not detected Not more than 890
12 Hexanes Not detected Not more than 290