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Table 4 LOD and LOQ data

From: Quantification of organic volatile impurities in Oseltamivir phosphate drug substances by head space gas chromatography

Name of OVI

LOD

 LOQ

Conc. (ppm)

S/N ratio

Conc. (ppm)

S/N ratio

Methanol

16.52

10.5

54.06

10.5

Ethanol

14.53

4.5

48.6

4.5

Acetonitrile

20.78

27.1

66.49

27.1

IPA

6.01

4.3

20.03

4.3

DCM

18.04

3.3

54.13

3.3

MTBE

1.5

3.2

5.51

3.2

Ethyl acetate

6

3.3

20.01

3.3

THF

3.27

3.1

10.89

3.1

1,4-Dioxane

15.2

3.5

49.4

3.5

DMF

80.13

3.4

267.09

3.4

Toluene

4.05

4.7

13.49

4.7

Hexanes

0.88

4.4

2.94

4.4