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Table 2 Extraction recovery results for ELX and RFX

From: Validation of the HPLC–PDA method for detection of eluxadoline and rifaximin in rat plasma and application in a pharmacokinetic study

Analytes Spiked conc.level (ng mL−1) Area response (n = 6) Extraction recovery (%) CV (%)
Extracted mean response Post extracted mean response
ELX LQC (50.0) 65,540 67,563 97.0 0.68
MQC (100.0) 130,424 142,522 91.5 0.16
HQC (150.0) 195,784 208,552 93.8 0.31
RFX LQC (100.0) 120,553 122,549 98.3 0.17
MQC (200.0) 240,481 262,371 91.6 0.13
HQC (300.0) 362,942 380,569 95.3 0.83