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Table 5 Pharmacokinetic parameters

From: Validation of the HPLC–PDA method for detection of eluxadoline and rifaximin in rat plasma and application in a pharmacokinetic study

Parameter Analytes
RFX ELX
t1/2 (h) 5.0 5.0
tmax (h) 1.5 1.5
cmax (ng/mL) 95.2 179.3
AUC0-t (ng h/mL) 245 463
AUC0-∞ (ng h/mL) 245 463
AUCt-∞ (ng h/mL) 11.9 23.8