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Table 4 Summary regression analysis results

From: Formulation of oxybutynin chloride microparticle-loaded suppositories: in vitro characterization and in vivo pharmacokinetic study

Models

R2

Adjusted R2

Predicted R2

SD

% CV

Response Y1

% production yield

Linear model

Eqh Y1 = 89.05 + 3.82X1 − 1.16X2

0.8125

0.7750

0.6600

1.48

1.67

Response Y2

%EE

Linear model

Eqh Y2 = 89.58 + 5.71 − 0.085X2

0.7349

0.6819

0.4933

2.66

2.97

Response Y3

% mucoadhesion strength

2FI

Y3 = 89.69 +  + 3.82 X1 − 0.76 X2 − 1.28X1X2

0.8942

0.8590

0.8207

1.13

1.26