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Table 5 Results of ANOVA for measured response

From: Formulation of oxybutynin chloride microparticle-loaded suppositories: in vitro characterization and in vivo pharmacokinetic study

Parameters

DF

SS

MS

F

Significance

Adeq. Prec

PRESS

P

Production yield

 Model

2

95.48

47.74

21.67

0.002

13.959

39.96

Significant

 Residual

10

22.03

2.20

–

–

–

–

–

 Total

12

117.51

49.94

–

–

–

–

–

Entrapment efficiency

 Model

2

195.67

97.83

13.86

0.0013

9.081

134.92

Significant

 Residual

10

70.58

7.06

–

–

–

–

–

 Total

12

266.25

104.89

–

–

–

–

–

Mucoadhesive strength

 Model

3

97.40

32.47

25.36

0.0001

16.235

19.53

Significant

 Residual

9

11.52

1.28

–

–

–

–

–

 Total

12

108.91

33.75

–

–

–

–

–