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Table 7 Forced degradation study

From: Stability-indicating RP-HPLC method development and validation for estimation of Mupirocin calcium in bulk and in pharmaceutical formulation

Exposure condition Exposure time Temperature Degradant peak Rt (min) % Degradation
0.1 N HCl 6 h 60 °C (Reflux) 3 5.56,6.54, 8.56 83.99
0.1 N NaOH 6 h 60 °C (Reflux) 3 5.23,5.50,7.59 79.04
H2O2 (10%) 24 h R.T. 1 5.41 24.11
Light 12 h Sunlight 1 5.42 11.20