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Table 7 Forced degradation study

From: Stability-indicating RP-HPLC method development and validation for estimation of Mupirocin calcium in bulk and in pharmaceutical formulation

Exposure condition

Exposure time

Temperature

Degradant peak

Rt (min)

% Degradation

0.1 N HCl

6 h

60 °C (Reflux)

3

5.56,6.54, 8.56

83.99

0.1 N NaOH

6 h

60 °C (Reflux)

3

5.23,5.50,7.59

79.04

H2O2 (10%)

24 h

R.T.

1

5.41

24.11

Light

12 h

Sunlight

1

5.42

11.20