Fig. 1From: Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseasesWith the help of a microprocessor complex in the nucleus, pri-miRNA is transformed to pre-miRNA. After that, pre-miRNA is transferred to the cytoplasm by exportin 5 and miRNA duplex formation occurs. Then, using RISC assembly, the miRNA duplex was transformed into mature miRNABack to article page