Skip to main content

Table 3 Involvement of vectors in miRNA-based delivery

From: Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases

Vector

Size

Structure

Influence on cells

AAV

~ 4.7 kb

Protein capsid with ss DNA

Dividing and non-dividing cells

Retroviruses

~ 7 to 11 kb

Lipid layer ss RNA

Only dividing cells

Lentiviruses

~ 8 kb

Protein capsid ss RNA

Dividing and non-dividing cells