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Table 3 Composition and responses of the full-factorial design

From: Promising role of topical caffeine mesoporous gel in collagen resynthesis and UV protection through proline assessment

Formula

Composition*

Responses

Caffeine concentration (CAFF. %)

Carrot oil concentration (CARR. %)

Raspberry oil concentration (RASP. %)

Q24 (μg/cm2) (A)

Kp (cm/hr) (B)

Jss (μg/cm2/hr.) (C)

SYL-C1

1

0

0

369.29 ± 61.94

7.50 ± 0.98

30 ± 2.93

SYL-C2

1

5

0

307.10 ± 50.78

5.38 ± 0.85

21.5 ± 1.34

SYL-C3

1

0

5

350.95 ± 45.91

5.00 ± 0.56

20.00 ± 3.01

SYL-C4

1

5

5

757.76 ± 55.21

5.85 ± 0.69

23.40 ± 0.99

SYL-C5

3

0

0

1216.52 ± 120.67

6.19 ± 1.04

74.25 ± 10.30

SYL-C6

3

5

0

1731.13 ± 90.39

9.67 ± 1.99

116 ± 12.94

SYL-C7

3

0

5

2038.15 ± 120.34

7.28 ± 1.09

87.4 ± 7.63

SYL-C8

3

5

5

3174.08 ± 201.33

11.50 ± 0.95

138 ± 10.01

SYL-C9

5

0

0

2820.52 ± 190.10

7.95 ± 1.00

159 ± 15.55

SYL-C10

5

5

0

2322.66 ± 301.14

10.27 ± 2.03

205.4 ± 8.99

SYL-C11

5

0

5

2693.32 ± 120.33

7.80 ± 0.87

156 ± 25.08

SYL-C12

5

5

5

5163.844 ± 208.11

15.78 ± 2.34

315.6 ± 16.67

  1. * All formulations contain 10% Lanette N, 5% glycerin, 5% propylene glycol, 5% wheat germ oil, 2.5% total essential oil blend (1.25% tea tree oil, 0.75 peppermint oil, and 0.5% sandalwood oil), 0.5% alpha-tocopherol, 0.15% methyl paraben, 0.3% propyl paraben, and 0.1% butylated hydroxytoluene