Future Journal of Pharmaceutical Sciences

Table 3 Stability study of optimized batch pirfenidone nanoparticles

From: Preparation and evaluation of pirfenidone loaded chitosan nanoparticles pulmonary delivery for idiopathic pulmonary fibrosis

Evaluation parameter	Time period for sampling
Evaluation parameter	Initial	After 1 month	After 3 months	After 6 months
Particle size (nm)	440.8 ± 3.9	459.3 ± 3.8	459.3 ± 3.8	459.3 ± 3.8
Zeta potential (mV)	36.3 ± 0.8	37.7 ± 1.13	36.78 ± 2.01	40.4 ± 2.51
% Entrapment efficiency	32.76 ± 1.8	33.11 ± 1.39	34.26 ± 1.69	31.6 ± 1.28
PDI	0.121 ± 0.032	0.129 ± 0.052	0.123 ± 0.041	0.137 ± 0.071
% drug release at 8 h	86.53 ± 3.45	85.83 ± 1.87	89.32 ± 2.14	87.96 ± 2.01
% drug release at 12 h	95.25 ± 2.84	94.89 ± 1.66	94.67 ± 2.16	96.19 ± 1.86

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