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Table 2 List of the microsponge-based drug delivery system marketed products

From: Microsponges: a breakthrough tool in pharmaceutical research

S. No.

Marketed product name

Ingredients

Manufacturer

Applications

References

1

Ultra guard

Dimethicone

Scott Paper Company

This formulation can prevent rashes on the skin caused by diaper use; it is also hypoallergenic and contains skin protectants

[5, 8, 29]

2

Salicylic peel 30

30% Salicylic acid

Biomedic

Removing dead skin cells without causing injury to healthy skin

[5, 8, 29]

3

NeoBenz®Micro

Benzoyl peroxide/methyl methacrylate/glycol

Intendis Inc. Morristown NJ07962 USA

It has antibacterial effects and is also a keratolytic agent

[5, 8, 29]

4

Retin-A-micro

0.1% and 0.04% Tretinoin, methyl methacrylate/glycol dimethacrylate, base is of aqueous gel

Biomedic Sothys

Fine lines and wrinkles on the skin can be minimised, skin discolouration due to ageing can be decreased, and skin smoothness can be improved

[5, 8, 29]

5

Salicylic Peel 20

Salicylic acid 20%

Biophora

Improvement may be noted in the fine lines; acne and pigmentation are reduced

[5, 8, 29]

6

Line eliminator DUAL RETINOL FACIAL TREATMENT

Vitamin A

Biophopra

Improvement in pigmentation and acne, as well as a reduction in fine wrinkles

[5, 8, 29]

7

Dermalogica oil control lotion

Niacinamide, yeast extract, caffeine, zinc gluconate, biotin, enantia chlorantha bark extract, and salicylic acid

John and Ginger dermalogica skin care products

To reduce the greasy sheen on the skin's surface

[5, 8, 29]

8

Carac cream

0.5% Fluorouracil, 0.35% methyl methacrylate/glycol dimethacrylate cross-polymer and dimethicone

Avon

Reduces the appearance of fine lines, wrinkles, and age-related discolouration of the skin

[5, 8, 29]

9

EpiQuin Micro

Hydroquinone and retinol

SkinMedica Inc.

To minimise skin irritation, MDS gently distribute the medicine to the skin with continued exposure

[5, 8, 29]

10

Retinol 15-night cream

Pure retinol and vitamin A

Sothys

Continuous use of Retinol 15-night cream results in visible improvements in wrinkles and fine lines reduction, apparent improvement in skin discolouration caused by ageing, and increased skin smoothness

[5, 8, 29]

11

LactrexTM12% moisturising cream

12% Lactic acid, ammonium lactate, water, and glycerine

SDR Pharmaceuticals Inc., Andover, NJ, USA, 07,821

This microsponge preparation is easy to apply and delivers long-lasting skin moisturisation. The water and glycerine incorporated in the preparation serve to make the skin softer and to offer moisturisation to dry, flaky, and cracked skin

[5, 8, 29]