From: Experimental design approach, screening and optimization of system variables, analytical method development of flurbiprofen in nanoparticles and stability-indicating methods for high-pressure liquid chromatography
Name
Units
Levels
Low (− 1)
High (+ 1)
MeOH conc
%
80
82
Flow rate
ml/min
1
1.2
Temperature
C
25
26
Wavelength
nm
245
247
pH
–
2.5
3