Table 3 Full factorial design matrix (in coded level) along with optimized formulation and experimental data
Factor 1 | Factor 2 | Factor 3 | Response 1 | Response 2 | Response 3 | Response 4 | ||
|---|---|---|---|---|---|---|---|---|
Std | Run | A:Flow Rate | B:Temp | C:Methanol | RT | PA | TF | TP |
ml/min | Celcius | % | Min | AUC | ||||
17 | 1 | 1.1 | 25 | 82.5 | 4.4 | 3925.52 | 0.72 | 9703 |
12 | 2 | 1.2 | 20 | 82.5 | 4 | 3604.91 | 0.75 | 8948 |
4 | 3 | 1 | 22.5 | 80 | 5.51 | 4321.57 | 0.72 | 10,240 |
18 | 4 | 1.2 | 25 | 82.5 | 4.04 | 3596.22 | 0.74 | 9050 |
14 | 5 | 1.1 | 22.5 | 82.5 | 4.49 | 3931.8 | 0.73 | 9576 |
2 | 6 | 1.1 | 20 | 80 | 5.02 | 3935.56 | 0.73 | 9202 |
10 | 7 | 1 | 20 | 82.5 | 4.95 | 4309.67 | 0.72 | 9981 |
27 | 8 | 1.2 | 25 | 85 | 3.69 | 3596.32 | 0.74 | 8684 |
16 | 9 | 1 | 25 | 82.5 | 4.85 | 4322.46 | 0.72 | 10,175 |
25 | 10 | 1 | 25 | 85 | 4.39 | 4328.81 | 0.72 | 10,165 |
7 | 11 | 1 | 25 | 80 | 5.61 | 4315.05 | 0.74 | 10,901 |
15 | 12 | 1.2 | 22.5 | 82.5 | 4.06 | 3592.36 | 0.74 | 8926 |
1 | 13 | 1 | 20 | 80 | 5.88 | 4319.99 | 0.73 | 9774 |
26 | 14 | 1.1 | 25 | 85 | 3.84 | 3922.21 | 0.73 | 9378 |
24 | 15 | 1.2 | 22.5 | 85 | 3.54 | 3599.88 | 0.74 | 8819 |
13 | 16 | 1 | 22.5 | 82.5 | 4.91 | 4319.04 | 0.72 | 10,110 |
20 | 17 | 1.1 | 20 | 85 | 3.9 | 3916.94 | 0.73 | 9409 |
22 | 18 | 1 | 22.5 | 85 | 4.25 | 4311.75 | 0.71 | 10,007 |
6 | 19 | 1.2 | 22.5 | 80 | 4.58 | 3596.63 | 0.74 | 9054 |
8 | 20 | 1.1 | 25 | 80 | 4.91 | 3937.21 | 0.73 | 9557 |
3 | 21 | 1.2 | 20 | 80 | 4.68 | 3596.83 | 0.75 | 9687 |
11 | 22 | 1.1 | 20 | 82.5 | 4.5 | 3933.82 | 0.73 | 9407 |
5 | 23 | 1.1 | 22.5 | 80 | 4.98 | 3953.49 | 0.73 | 9556 |
23 | 24 | 1.1 | 22.5 | 85 | 3.88 | 3919.34 | 0.73 | 9319 |
21 | 25 | 1.2 | 20 | 85 | 3.75 | 3603.87 | 0.74 | 8730 |
19 | 26 | 1 | 20 | 85 | 4.22 | 4323.15 | 0.72 | 9713 |
9 | 27 | 1.2 | 25 | 80 | 4.68 | 3596.83 | 0.75 | 9687 |