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Future Journal of Pharmaceutical Sciences

Table 5 ANOVA results for Response 1: RT

From: Experimental design approach, screening and optimization of system variables, analytical method development of flurbiprofen in nanoparticles and stability-indicating methods for high-pressure liquid chromatography

Source

Sum of squares

d. f

Mean square

F-value

p-value

 

Model

9.34

4

2.33

268.29

 < 0.0001

Significant

A-Flow rate

3.17

1

3.17

363.99

 < 0.0001

 

C-Methanol

6.00

1

6.00

689.33

 < 0.0001

 

AC

0.1160

1

0.1160

13.34

0.0014

 

A2

0.0567

1

0.0567

6.52

0.0181

 

Residual

0.1914

22

0.0087

   

Cor Total

9.53

26

    
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