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Table 1 Optimization technique with levels and factors

From: Development and evaluation of ultradeformable vesicles loaded transdermal film of boswellic acid

Independent factors Coded value Uncoded value
  Low Medium High Low Medium High
X1 = Amount of Lecithin (mg) − 1 0  + 1 150 200 250
X2 = Conc. Of Tween 80 (%) − 1 0  + 1 0.5 0.75 1
Dependent factors
Y1 = Vesicle size (nm)    Y2 = Entrapment efficiency (%)