Fig. 16From: Elucidation of possible mechanisms of the antidiabetic potential of Zn-loaded Bryophyllum pinnatum (Lam.) extracts in experimental animal modelsRole of zinc ion in diabetes. BPSAL along with ZnSO4 when enters into the cells converts into Zn + + ions and extracts when enters into the cell disturb the cell potential and positive ions inside the cell capture the various ROS such as OH−, NO−, H2O2, etc., which causes the degradation of ribosomes, cell membrane disruption, DNA damage and protein denaturation etc.Back to article page