Table 3 Composition of a transdermal patch according to factorial design
From: Primaquine-loaded transdermal patch for treating malaria: design, development, and characterization
Formulation code | Components (% w/w of total polymer weight of 300 mg) | ||||
|---|---|---|---|---|---|
Primaquine | Pmix (R1) | DMSO (R2) | Plasticizer (PEG 400) | Solvent (Ethanol: Water) | |
F1 | 100 (300 mg) | 1:1 (− 1) | 10 (− 1) | 30 | 1:1 |
F2 | 100 (300 mg) | 1:1 (− 1) | 15 (0) | 30 | 1:1 |
F3 | 100 (300 mg) | 1:1 (− 1) | 20 (1) | 30 | 1:1 |
F4 | 100 (300 mg) | 1:2 (0) | 10 (− 1) | 30 | 1:1 |
F5 | 100 (300 mg) | 1:2 (0) | 15 (0) | 30 | 1:1 |
F6 | 100 (300 mg) | 1:2 (0) | 20 (1) | 30 | 1:1 |
F7 | 100 (300 mg) | 1:3 (1) | 10 (− 1) | 30 | 1:1 |
F8 | 100 (300 mg) | 1:3 (1) | 15 (0) | 30 | 1:1 |
F9 | 100 (300 mg) | 1:3 (1) | 20 (1) | 30 | 1:1 |