Table 4 Optimum conditions obtained by derringer’s desirability approach
Independent variable | Coded values | Estimated values | Results obtained | |||||
|---|---|---|---|---|---|---|---|---|
Droplet size (Y1) | PDI (Y2) | Percent drug release at 15 min (Y3) | Trial | Droplet size (Y1) | PDI (Y2) | Percent drug release at 15 min (Y3) | ||
A—Amount of oil | 0.078 | 189.46 | 0.27 | 21.64 | S1 | 192.43 | 0.30 | 20.96 |
B—Amount of Surfactant | 0.000 | S2 | 194.74 | 0.29 | 19.88 | |||
C—Amount of Co-surfactant | 0.922 | S3 | 191.68 | 0.28 | 21.24 | |||