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Table 1 Phytochemical constituents compounds identified and biological activities of dichloromethane Clinacanthus nutans leaf extracts by gas chromatography–mass spectrometry (GC–MS)

From: Exploring Clinacanthus nutans leaf different solvent extracts on antiproliferative effects induced metastasis through apoptosis and cell cycle against MCF-7 human breast cancer cell lines

No

Identified/similar compounds

Retention time (min)

Peak area (%)

Molecular weight (g mol−1)

Biological activities

Molecular formula

1

Pentadecanoic acid, 14-methyl-methyl ester

19.940

3.40

270.4

No activity reported

C17H34O2

2

Hexadecanoic acid, methyl ester

19.940

3.40

270.45

Antioxidant, flavour, hypocholesterolemic, nematicide, antiandrogenic, cancer preventive

C17H34O2

3

Diphenyl sulfone

20.260

0.36

218.27

Antimicrobial, Antibacterial and antifungal

(C6H5)2SO2

4

9,12-Octadecadienoic acid, methyl ester

24.849

0.96

294.4721

Antiinflammatory, hypocholesterolemic, cancer preventive, nematicide, hepatoprotective, insectifuge, antihistaminic, antieczemic, antiacne, antiandrogenic, antiarthritic, anticoronary

C19H34O2

5

9,12-Octadecadienoic acid (Z,Z)-, methyl ester

24.849

0.96

294.5

Antiinflammatory, hypocholesterolemic, cancer preventive, nematicide, hepatoprotective, insectifuge, antihistaminic, antieczemic, antiacne, antiandrogenic, antiarthritic, anticoronary

C19H34O2

6

9,15-Octadecadienoic acid, methyl ester,(Z,Z)-

24.849

0.96

294.5

Hypercholesterolemic, antiarthritic, hepatoprotective, antiandrogenic, antihelmintic, antihistaminic. Antieczemic

C19H34O2

7

9,12,15-Octadecatrienoic acid, methyl ester

25.119

3.58

292.4562

Antiinflammatory, hypocholesterolemic and antiarthritic

C19H32O2

8

9,12,15-Octadecatrien-1-ol,(Z,Z,Z)-

25.119

3.58

264.4

Antimicrobial

C18H32O

9

9,12,15-Octadecatrienoic acid, methyl ester, (Z,Z,Z)

25.119

3.58

292.4562

Antiinflammatory, hypocholesterolemic and antiarthritic cancer preventive, hepatoprotective, antioxidant and hypocholesterolemic

C19H32O2

10

Octadecanoic acid, methyl ester

26.097

1.25

298.5

Antiinflammatory, hypocholesterolemic and antiarthritic

C19H38O2

11

.gamma.-Sitosterol

39.188

14.21

414.718

Antidiabetic

C29H52O2

12

Stigmasterol, 22,23-dihydro-

39.188

14.21

412.7

Antihypercholesterolemic activity, antiinflammatory, anticancer

C29H48O

13

.beta.-Sitosterol

39.188

14.21

414.718

Antihypercholesterolemia, anticancer

C29H50O

14

.beta.-Amyrin

42.275

7.36

426.7

Antinociceptive and antiinflammatory

C30H50O

15

.alpha.-Amyrin

42.275

7.36

426.7

Antinociceptive and antiinflammatory

C30H50O

16

9-Octadecenamide, (Z)-

45.683

1.79

281.48

Antiinsomnia

C18H35NO