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Future Journal of Pharmaceutical Sciences

Table 5 Effect of fractions of C. paniculatum on absolute ethanol-induced ulcer in rats

From: Gastroprotective effects of Combretum paniculatum (Combretaceae) leaf extract and fractions on absolute ethanol-induced gastric ulcer in rats

Treatment

Dose (mg/kg)

Ulcer index

Percentage protection

3% Tween 80

5 ml/kg

0.90 ± 0.04

–

Omeprazole

20

0.38 ± 0.12*

57.78

HFCP

100

0.32 ± 0.10**

64.44

 

200

0.18 ± 0.13***

80.00

EAFCP

100

0.53 ± 0.11

41.11

 

200

0.38 ± 0.14*

57.78

BFCP

100

0.24 ± 0.04**

73.33

 

200

0.28 ± 0.14**

68.89

  1. Values are expressed as mean ± SEM; n = 6
  2. HFCP n-hexane fraction, EAFCP ethyl acetate fraction, BFCP butanol fraction
  3. *, **, ***P < 0.05, 0.01, 0.001 significant difference relative to the negative control
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