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Table 4 Effects of N. canescens extracts on biochemical parameters and serum enzymes in alloxan-induced diabetic rats

From: Nelsonia canescens (Acanthaceae) aqueous extract and partitioned fractions ameliorates type-2 diabetes in alloxan-induced diabetic rats

Parameters

AQ 50

AQ 300

EA 50

EA 300

ME 50

ME 300

Glibenclamide

Diabetic control

Normal control

Total Protein (mg/dL)

6.91 ± 0.36a

6.76 ± 0.56a

7.22 ± 0.06ab

9.92 ± 3.10c

9.61 ± 1.48c

8.42 ± 1.14b

6.24 ± 0.27a

8.30 ± 0.10b

7.01 ± 0.36ab

Albumin (mg/dL)

4.09 ± 0.41a

4.62 ± 0.36a

4.33 ± 0.50a

4.96 ± 0.33ab

5.19 ± 0.29b

4.53 ± 0.07a

3.76 ± 0.35a

4.75 ± 0.12a

4.61 ± 0.13a

Creatinine (mg/dL)

1.29 ± 0.57a

1.81 ± 0.61a

273.16 ± 10.31c

211.28 ± 25.80c

9.79 ± 1.84b

2.67 ± 0.49a

203.61 ± 43.64c

401.56 ± 18.34d

264.76 ± 40.17c

ALT (U/L)

297.02 ± 16.06a

237.50 ± 40.81a

202.44 ± 17.63a

364.21 ± 31.33b

547.64 ± 65.42c

247.74 ± 17.02a

272.27 ± 13.83a

383.66 ± 16.42b

215.25 ± 46.11a

AST (U/L)

179.16 ± 25.05b

128.47 ± 33.71b

0.41 ± 0.04a

1.98 ± 0.86a

6.39 ± 80.23d

4.45 ± 92.60c

2.41 ± 0.79a

1.74 ± 0.21a

2.30 ± 0.55a

  1. Values are expressed in mean ± standard error of mean, n = 5. Values with the same superscript on the same row have no significant difference at p < 0.05
  2. Key: AQ = Aqueous extract, EA = Ethylacetate fractions, ME = Methanol fractions