QSAR, simulation techniques, and ADMET/pharmacokinetics assessment of a set of compounds that target MAO-B as anti-Alzheimer agent

Future Journal of Pharmaceutical Sciences

Table 4 Y-randomization assessment of MLR

Model type	R	R²	Q² (LOO)
Original	0.827819	0.685284	0.574515
Random 1	0.412459	0.170122	− 0.48832
Random 2	0.47985	0.230256	− 0.51132
Random 3	0.255063	0.065057	− 0.741
Random 4	0.279267	0.07799	− 0.35473
Random 5	0.411131	0.169028	− 0.69774
Random 6	0.366618	0.134409	− 0.27287
Random 7	0.422091	0.178161	− 0.34895
Random 8	0.484999	0.235224	− 0.18176
Random 9	0.515376	0.265613	− 0.03472
Random 10	0.348056	0.121143	− 0.29197
Average R	0.436612
Average R²	0.212026
Average Q² (LOO)	− 0.30444
cRp²	0.601116